Genetics (GEN)
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Course numbers with the # symbol included (e.g. #400) have not been taught in the last 3 years.
GEN 604 - Principles of Genetics
Credits: 0 or 4
Chemical structure of genetic material, gene recombination, mutation, and chromosome mapping. Gene expression and regulation; recombinant DNA; evolutionary, quantitative, and population genetics. College math or statistics suggested.
Prerequisite(s): (( (BIOL 411 with a minimum grade of D- or BIOL 411H with a minimum grade of D- or BIOL 413 with a minimum grade of D-) and (BIOL 412 with a minimum grade of D- or BIOL 412H with a minimum grade of D- or BIOL 414 with a minimum grade of D-)) or BMS 507 with a minimum grade of D-) and CHEM 403 with a minimum grade of D- and (CHEM 404 with a minimum grade of D- or CHEM 404H with a minimum grade of D-).
Equivalent(s): BIOL 604
Grade Mode: Letter Grading
GEN 606 - Genetics Lab
Credits: 4
Hands-on experience with some of the important model organisms used for research in genetics (fruit flies, bacteria, yeast, nematodes, and plants). Investigation of fundamental genetic concepts in the laboratory, experience with transmission and molecular genetic techniques, introduction to bioinformatics, analysis and interpretation of data.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Grade Mode: Letter Grading
Special Fee: Yes
GEN 704 - Genetics of Prokaryotic Microbes
Credits: 5
Maintenance, exchange, and expression of genetic material in bacteria and their viruses. Historical overview of the role microbial genetics played in development of modern molecular biology. Contemporary perspective on methods used to understand the function of genes and their applications to basic science, biomedical research, and biotechnology. Lab.
Attributes: Writing Intensive Course
Prerequisite(s): BMS 503 with a minimum grade of D- and BMS 504 with a minimum grade of D- and GEN 604 with a minimum grade of D-.
Grade Mode: Letter Grading
Special Fee: Yes
GEN 705 - Population Genetics
Credits: 3
Exploration of the forces (mutations, selection, random drift, inbreeding, assortative mating) affecting the frequency and distribution of genetic variation in natural populations. Quantifying the structure of populations. Methods of analysis for theoretical and practical applications.
Prerequisite(s): GEN 604 with a minimum grade of D- and BIOL 528 with a minimum grade of D-.
Equivalent(s): PBIO 705, ZOOL 665, ZOOL 705
Mutual Exclusion: No credit for students who have taken NR 664.
Grade Mode: Letter Grading
GEN 706 - Human Genetics
Credits: 4
Genetic basis of human traits and diseases including both traditional methods of diagnosis and contemporary molecular genetic approaches stemming from the human genome project. Case studies exemplify common practices in human genetic counseling and integrate the scientific basis of diagnosis with the special ethical implications of human genetic analysis.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): ANSC 706, BCHM 706
Grade Mode: Letter Grading
GEN 711 - Genomics and Bioinformatics
Credits: 0 or 4
Methods, applications, and implications of genomics--the analysis of whole genomes. Medical, ethical and legal implications of genomic data. Computer lab provides exposure and experience in a range of bioinformatics approaches used in genome analysis. Computer Lab.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): GEN 711W
Grade Mode: Letter Grading
GEN 711W - Genomics and Bioinformatics
Credits: 0 or 4
Methods, applications, and implications of genomics--the analysis of whole genomes. Microbial, plant and animal genomics are addressed, as well as medical, ethical and legal implications. The lab provides exposure and experience on a range of bioinformatics approaches--the computer applications used in genome analysis. Lab.
Attributes: Writing Intensive Course
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): BCHM 711, BCHM 715, GEN 711, MICR 711, MICR 715
Grade Mode: Letter Grading
GEN 712 - Programming for Bioinformatics
Credits: 5
Development of programming skills that enable life science students to ask fundamental biological questions that require computers to automate repetitive tasks and handle query results efficiently. Topics include: computer values of important parameters of biological sequence data; pattern search and motif discovery scripts; accessing, querying, manipulating, retrieving, parsing, analyzing, and saving data from local and remote databases. Computer Lab.
Prerequisite(s): GEN 604 with a minimum grade of D- and GEN 711 with a minimum grade of D-.
Grade Mode: Letter Grading
GEN 713 - Microbial Ecology and Evolution
Credits: 4
Evolutionary and ecological forces that generate the tremendous diversity of microbial life on Earth with emphasis on viruses, archaea and bacteria. Functional roles of microorganisms, their population dynamics and interactions, and their mechanisms of evolutionary change in a variety of environmental settings, including natural communities and laboratory microcosms.
Attributes: Writing Intensive Course
Prerequisite(s): GEN 604 with a minimum grade of D- and BMS 503 with a minimum grade of D- and BMS 504 with a minimum grade of D-.
Equivalent(s): MICR 713
Grade Mode: Letter Grading
GEN 714 - Personal Genomics
Credits: 4
Analysis and implications of personal genomic data is the focus of this course. Students understand and appreciate all aspects of the availability of personal genomic information and tools including scientific, medical, social, ethical and legal issues. Students have the opportunity to analyze their own individual genome to one of the publicly available genomes to learn about all various aspects of this emerging field. The course will be an entirely online format.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Grade Mode: Letter Grading
GEN 715 - Molecular Evolution
Credits: 4
Rates and patterns of evolutionary change in biomolecules. Forces affecting the size and structure of genomes. Molecular mechanisms of organismal evolution. Emphasizes integrating evidence from biochemistry, molecular genetics and organismal studies. Methods for reconstructing phylogeny from molecular sequences. Some knowledge of statistics recommended. Computer Lab.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): ZOOL 715
Grade Mode: Letter Grading
GEN 717 - Molecular Microbiology
Credits: 5
Fundamental physiological and metabolic processes of archaea, bacteria and fungi with a strong emphasis on prokaryotes. Literature-based course. Topics include regulation and coordination of microbial metabolism, bacterial cell cycle, global control of gene expression, signal transduction, and microbial cell differentiation. Lab.
Attributes: Writing Intensive Course
Prerequisite(s): BMS 503 with a minimum grade of D- and BMS 504 with a minimum grade of D- and GEN 604 with a minimum grade of D-.
Equivalent(s): MICR 717
Grade Mode: Letter Grading
Special Fee: Yes
GEN 721 - Comparative Genomics
Credits: 4
Explores the central questions and themes in contemporary comparative genomics, including genome biology, phylogenomics, human origins, population genomics, and ecological genomics. Provides the conceptual framework required to evaluate new work in this fast-changing field.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Grade Mode: Letter Grading
GEN 725 - Population Genetics Lab
Credits: 2
Hands-on approach to exploration of evolutionary forces affecting the frequency and distribution of genetic variation in natural populations. Wet lab techniques include DNA extraction, restriction enzyme digestion, PCR, DNA fragment size-selection. Computational skills include high-throughput sequencing data control, identifying allelic variants, and generation of population genetic summary statistics.
Co-requisite: GEN 705
Prerequisite(s): GEN 604 with a minimum grade of D- and BIOL 528 with a minimum grade of D-.
Grade Mode: Letter Grading
GEN 771 - Molecular Genetics
Credits: 4
Structure, organization, replication, dynamics, and expression of genetic information in eukaryotes. Focus on molecular genetic and epigenetic mechanisms of gene expression and its control; molecular genetic control of cell division and differentiation during development.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Grade Mode: Letter Grading
GEN 772 - Evolutionary Genetics of Plants
Credits: 4
Mechanisms of genetic change in plant evolution, both in nature and under human influence. Topics include neo-Darwinian theory; speciation and hybridization; origins and co-evolution of nuclear and organelle genomes; gene and genome evolution; transposable elements; chromosome rearrangements; polyploidy; genetic modification. Lab introduces methods in information gathering, bioinformatics, genome analysis, plant breeding, and genetic manipulation. Lab.
Attributes: Writing Intensive Course
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): PBIO 772
Grade Mode: Letter Grading
GEN #774 - Techniques in Plant Genetic Engineering and Biotechnology
Credits: 4
Theory and hands-on experience with techniques used in plant genetic engineering, including cell and tissue culture, gene cloning, and analysis of foreign gene expression. Discussion of role of plant biotechnology in sustainable agriculture and climate change; modifying plants for better nutrition and stress response, environmental remediation , and production of pharmaceuticals; controversies associated with this technology. Lab.
Prerequisite(s): GEN 604 with a minimum grade of D-.
Equivalent(s): PBIO 774, PBIO 775
Grade Mode: Letter Grading
Special Fee: Yes
GEN 790 - Undergraduate Teaching Experience
Credits: 1-4
Provide academic support to graduate teaching assistants or faculty in preparing, presenting, and executing Genetics lectures or labs.
Repeat Rule: May be repeated for a maximum of 4 credits.
Equivalent(s): MICR 790
Grade Mode: Letter Grading
GEN 795 - Investigations in Genetics
Credits: 1-4
Advanced research or scholarly projects developed and conducted under the supervision of a faculty member. Provides the opportunity to apply advanced knowledge and techniques of the major to a specific problem or question.
Repeat Rule: May be repeated for a maximum of 4 credits.
Equivalent(s): GEN 795W
Grade Mode: Letter Grading
GEN 795W - Investigations in Genetics
Credits: 1-4
Advanced research or scholarly projects developed and conducted under the supervision of a faculty member. Provides the opportunity to apply advanced knowledge and techniques of the major to a specific problem or question.
Attributes: Writing Intensive Course
Repeat Rule: May be repeated for a maximum of 4 credits.
Equivalent(s): GEN 795
Grade Mode: Letter Grading
GEN 799 - Senior Thesis
Credits: 1-4
Independent research project under the direction of a faculty sponsor for seniors in genetics. Final product is a written thesis. One or two semesters.
Attributes: Writing Intensive Course
Repeat Rule: May be repeated for a maximum of 8 credits.
Grade Mode: Letter Grading
GEN 799H - Honors Senior Thesis
Credits: 1-4
Independent research project under the direction of a faculty sponsor for seniors in genetics and in the Honors Program. Final product is a written thesis. One or two semesters.
Attributes: Honors course; Writing Intensive Course
Repeat Rule: May be repeated for a maximum of 8 credits.
Grade Mode: Letter Grading