Biochemistry, Molecular & Cellular Biology (BMCB)

BMCB 401 - Professional Perspectives in Biochemistry, Molecular and Cellular Biology

Credits: 1

Introduction to the fields of biochemistry, molecular and cellular biology. Explores professional opportunities for BMCB majors. Guest speakers from on- and off-campus present seminars and lead discussions on contemporary issues in subject area. Development of strategies for achieving professional goals. Cr/F.

Grade Mode: Credit/Fail Grading

BMCB #405 - Biotechnology Research Internship

Credits: 2

A 4-week (minimum) experiential learning internship in which students conduct independent laboratory-based research in an area of shared interest with a faculty mentor in the College of Life Sciences and Agriculture. Students gain first-hand experience conducting original research, incorporating direct observation, reflection, evaluation, and discussion. Permission required. Open to high school students only.

Grade Mode: Credit/Fail Grading

BMCB 501 - Biological Chemistry

Credits: 4

Survey of the molecular basis of life with a focus on the mechanisms of biochemical reactions in metabolic pathways, beginning with an overview of functional groups and organic reactions relevant for living organisms. Bioenergetics of carbohydrate, lipid, and nitrogen metabolic pathways. Prereq: CHEM 403 and CHEM 404, or CHEM 411.

Mutual Exclusion: No credit for students who have taken BMCB 658, BMCB 751, BMCB 752.

Grade Mode: Letter Grading

BMCB 605 - Principles of Cell Biology

Credits: 4

Cell and developmental biology of multicellular eukaryotic organisms. Structure and function of major cellular compartments; mechanisms of cellular communication and dynamics; embryonic development. Special topics: subcellular organization and function; membrane biogenesis; signal transduction; mitogenesis; apoptosis; autophagy; tumor suppressors and cell cycle regulation; cytokinesis; cytoskeletal dynamics; cellular shape and motility; stem cell biology; organogenesis; morphogenesis and patterning. Prereq: BIOL 411 and BIOL 412; CHEM 403 and CHEM 404.

Equivalent(s): BIOL 605, BSCI #735

Grade Mode: Letter Grading

BMCB 658 - General Biochemistry

Credits: 3

Comprehensive, introductory course emphasizing the cellular metabolism and the structure and function of proteins, nucleic acids, carbohydrates, and lipids. Prereq: BIOL 411; CHEM 545 and CHEM 546, or CHEM 547 and CHEM 548, or CHEM 651 and CHEM 652.

Co-requisite: BMCB 659

Equivalent(s): BMCB 658A

Mutual Exclusion: No credit for students who have taken BMCB 501.

Grade Mode: Letter Grading

BMCB 658A - General Biochemistry

Credits: 3

Comprehensive, introductory course emphasizing the cellular metabolism and the structure and function of proteins, nucleic acids, carbohydrates, and lipids. This course is intended for programs that do not require a biochemistry laboratory. Prereq: BIOL 411; CHEM 545 and CHEM 546, or CHEM 547 and CHEM 548, or CHEM 651 and CHEM 652.

Equivalent(s): BMCB 658

Mutual Exclusion: No credit for students who have taken BMCB 501.

Grade Mode: Letter Grading

BMCB 659 - General Biochemistry Lab

Credits: 2

Structured laboratory experiments that provide training in analytical and preparative techniques fundamental to modern biochemistry and molecular biology. Coreq: BMCB 658. Special fee.

Co-requisite: BMCB 658

Equivalent(s): BCHM 659, BMCB 659W

Grade Mode: Letter Grading

BMCB 659W - General Biochemistry Lab

Credits: 2

Structured laboratory experiments that provide training in analytical and preparative techniques fundamental to modern biochemistry and molecular biology. Coreq: BMCB 658. Special fee. UNHM only. Writing intensive.

Co-requisite: BMCB 658

Attributes: Writing Intensive Course

Equivalent(s): BCHM 659, BMCB 659

Grade Mode: Letter Grading

BMCB 750 - Physical Biochemistry

Credits: 3

Structure, interactions, and physical-chemical properties of biomolecules. Thermodynamic, kinetic, and spectroscopic methods for the study of proteins and nucleic acids. Prereq: CHEM 547 and CHEM 549 and CHEM 548 and CHEM 550 or equivalent; MATH 424B or equivalent; or permission.

Equivalent(s): BCHM 750

Grade Mode: Letter Grading

BMCB 751 - Principles of Biochemistry

Credits: 4

In-depth survey of biochemistry: macromolecular structure; structure and function of proteins, nucleic acids, carbohydrates, and lipids; introduction to metabolic pathways. Prereq: CHEM 547 and CHEM 548, or CHEM 651 and CHEM 652; or permission.

Equivalent(s): BCHM 751

Mutual Exclusion: No credit for students who have taken BMCB 501.

Grade Mode: Letter Grading

BMCB 752 - Principles of Biochemistry

Credits: 4

In-depth survey of biochemistry: metabolism of amino acids, nucleotides, carbohydrates and lipids; synthesis and regulation of macromolecules; molecular biology of the eukaryotic cell. Prereq: BMCB 751 or permission.

Equivalent(s): BCHM 752

Mutual Exclusion: No credit for students who have taken BMCB 501.

Grade Mode: Letter Grading

BMCB 753 - Cell Culture

Credits: 5

Principles and technical skills fundamental to the culture of animal and plant cells, tissues, and organs. Introduction to the techniques of sub-culturing, establishing primary cultures, karyotyping, serum testing, cloning, growth curves, cryopreservation, hybridoma formation and monoclonal antibody production, and organ cultures. Application of cell culture to contemporary research in the biological sciences. Prereq: BMS 503 and 504. Special fee. Lab.

Equivalent(s): ANSC 751, MICR 751, PBIO 751

Grade Mode: Letter Grading

BMCB 754 - Molecular Biology Research Methods

Credits: 5

Theory and application of current technologies to manipulate DNA. Hands-on research experience that includes DNA isolation and quantitation methods, cloning, PCR, DNA sequencing, and analysis of gene products. Prereq: GEN 604. Special fee. Lab. Writing intensive.

Attributes: Writing Intensive Course

Equivalent(s): BCHM 754, BSCI 765, GEN 754, PBIO 754

Grade Mode: Letter Grading

BMCB 755 - Protein Biochemistry Laboratory

Credits: 5

Application of modern approaches to the characterization and purification of proteins. Emphasis on recombinant protein production and purification, analytical techniques for characterization of proteins, enzyme kinetics, and molecular visualization of protein structure. Prereq: one semester of biochemistry or permission. Special Fee.

Attributes: Writing Intensive Course

Grade Mode: Letter Grading

BMCB 760 - Pharmacology

Credits: 4

Introduction to the basic principles and fundamental concepts of pharmacology, with a focus on molecular mechanisms and pathological basis of therapeutics and their curative effects. Topics include: foundations of pharmacology including pharmacodynamics and pharmacogenomics; drugs affecting other systems; chemotherapeutic drugs. Prereq: BMCB 658 or BMCB 751, or permission.

Mutual Exclusion: No credit for students who have taken BSCI 680.

Grade Mode: Letter Grading

BMCB 763 - Biochemistry of Cancer

Credits: 4

Evaluation of the hallmarks of cancer, including molecular mechanisms of carcinogenesis, roles of oncogenes and dysregulated cell development, function and metabolism, tumor immunology, and the biological basis of cancer therapy. Prereq: BMCB 658 or BMCB 751 or permission.

Equivalent(s): BCHM 763

Grade Mode: Letter Grading

BMCB 790 - Undergraduate Teaching Experience

Credits: 1-4

Provide academic support to graduate teaching assistants or faculty in preparing, presenting, and executing Biochemistry, Molecular and Cellular Biology lectures or labs. Permission required.

Repeat Rule: May be repeated for a maximum of 4 credits.

Grade Mode: Letter Grading

BMCB 794 - Protein Structure and Function

Credits: 4

Analysis of how the three-dimensional architecture of soluble and membrane proteins contributes to their biochemical function; methods for determining the structure of proteins; protein folding; protein targeting; mechanisms of enzyme catalysis. Computer resources used for protein modeling and structural prediction. Prereq: BMCB 658 or BMCB 751 or permission.

Equivalent(s): BCHM 794

Grade Mode: Letter Grading

BMCB 795 - Investigations in Molecular and Cellular Biology

Credits: 1-4

Advanced research or scholarly projects developed and conducted under the supervision of a faculty member. Provides the opportunity to apply advanced knowledge and techniques of the major to a specific problem or question. Permission required.

Repeat Rule: May be repeated for a maximum of 8 credits.

Equivalent(s): BCHM 795, BCHM 795W, BMCB 795W

Grade Mode: Letter Grading

BMCB 795W - Investigations in Molecular and Cellular Biology

Credits: 1-4

Advanced research or scholarly projects developed and conducted under the supervision of a faculty member. Provides the opportunity to apply advanced knowledge and techniques of the major to a specific problem or question. Permission required.

Attributes: Writing Intensive Course

Repeat Rule: May be repeated for a maximum of 8 credits.

Equivalent(s): BCHM 795, BCHM 795W, BMCB 795

Grade Mode: Letter Grading

BMCB 799 - Senior Thesis

Credits: 1-4

Independent research project under the direction of a faculty sponsor for seniors in biochemistry, molecular and cellular biology. Final product is a written thesis. One or two semesters. Permission required.

Attributes: Writing Intensive Course

Repeat Rule: May be repeated for a maximum of 8 credits.

Equivalent(s): BCHM 699, BCHM 799, BCHM 799H, BMCB 799H

Grade Mode: Letter Grading

BMCB 799H - Honors Senior Thesis

Credits: 1-4

Independent research project under the direction of a faculty sponsor for seniors in biochemistry, molecular and cellular biology and in the Honors Program. Final product is a written thesis. One or two semesters. Permission required.

Attributes: Honors course; Writing Intensive Course

Repeat Rule: May be repeated for a maximum of 8 credits.

Equivalent(s): BCHM 799, BCHM 799H, BMCB 799

Grade Mode: Letter Grading