Molecular and Evolutionary Systems Biology (Ph.D.)
The Ph.D. in Molecular and Evolutionary Systems Biology (MESB) is a coherently designed doctoral program that promotes interdisciplinary research, deep knowledge in specific disciplines, and technical, professional, and personal skills needed by 21st century scientists and educators . Graduates of the program are equipped for leadership roles in biotechnology and pharmaceutical companies, academic and government research laboratories, and successful careers in teaching and research at the college and university level.
Distinctive Features of the Program
- Emphasis on interdisciplinary research training including co-mentorship across traditional disciplines
- An innovative graduate curriculum that emphasizes ethical, legal and social implications of bioscience research
- Well-equipped research laboratories and core facilities on the UNH campus
- Laboratory rotations upon entry to the program to become familiar with different research laboratories
- Weekly graduate student seminar presentations, as well as a departmental seminar series of outside speakers
- Opportunities to gain teaching experiences as a Graduate Teaching Assistant
- Molecular and Cellular Biology
- Protein structure, function, and regulation
- Signal transduction pathways
- Molecular evolutionary genomics
- Genomics and bioinformatics
- Transcriptional and translational regulation
- Microbial ecology and evolution
- Students admitted to the Ph.D. Program are typically supported by Research Assistantships or Teaching Assistantships
- Internal summer and academic year fellowships are available to students on a competitive basis.
- Research directors in biotechnology and pharmaceutical industries
- Principle investigators in academic research labs and research institutes, state and federal government agencies
- Academic preparation for research and teaching roles in a college or university environment
- Completion of foundational courses in biology, chemistry (including organic chemistry), physics, and mathematics
- Otherwise well-qualified applicants can correct academic deficiencies with enrollment in appropriate courses or independent study during the first year of graduate studies
- Graduate Record Examination (GRE) scores (taken within the past five years)
- Applicants from non-English speaking countries must provide Test of English as a Foreign Language (TOEFL) scores
- International applicants living outside the U.S.A. should first complete a free online application
- Three letters of recommendation
Personal statement, including research interests and two or three potential MESB faculty thesis advisors.
Ph.D. Degree Requirements
Degree requirements for the MESB Ph.D. degree include a series of core courses in scientific communications, applied bioinformatics, and ethical, legal, and social implications of modern biotechnology, as well as a research proposal, qualifying examinations, and the completion of a dissertation.
Research Proposal and Oral Defense: No later than at the conclusion of the second full semester of dissertation research (typically the third semester if rotating) students prepare a succinct synopsis of their thesis project, with citations. The synopsis includes:
- Background: a summary of problem and general knowledge in the field.
- Hypotheses, Questions, and Relevance: articulates specific hypotheses, questions to be addressed, and importance of research.
- Approach: a general description of approaches with caveats, possible problems, alternative approaches, and resources of expertise.
- Timeline: a general timeline for completion of the work.
- Communication: potential audiences for the work (meetings, publications).
Students submit this proposal to their guidance committee who will read it and provide input in a committee meeting, which should take place no later than the end of their third semester. Upon review by the guidance committee, students must defend their proposal in an oral examination.
Qualifying Examination: The inter-disciplinarity inherent in the MESB graduate program requires that students integrate their training and research objectives across different fields of inquiry. This integration across fields is intended to foster unique perspectives on persistent questions in biology. To demonstrate the significance of the new perspectives inculcated by their research proposals, students must also submit an additional written qualifying examination. Written qualifying examinations may take the form of a review or synthesis article that emphasizes the integration of the research disciplines of the primary and secondary mentors and the significance of doing so given the problem. The specific format and outline of the written examination is to be determined by the guidance committee. Once complete, the written qualifying examination will be submitted to, and assessed by, the guidance committee on a pass/fail basis.
Advancement to Candidacy: The student is advanced to candidacy after the qualifying examination has been successfully passed and other requirements have been fulfilled.